Acellular dermis for facial soft tissue augmentation: preliminary report.

P. D. Costantino, S. Govindaraj, D. H. Hiltzik, D. Buchbinder, M. L. Urken

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


OBJECTIVE: To evaluate the efficacy of acellular dermis as a viable alternative for soft tissue augmentation in facial reconstruction. DESIGN: A prospective, nonrandomized observational study consisting of 10 patients who underwent soft tissue augmentation with acellular dermis. SETTING: A tertiary care university medical center in an urban setting. PATIENTS: Ten patients who had undergone soft tissue augmentation using acellular dermis participated in this study. Postimplantation follow-up was 17 to 36 months. INTERVENTION: The amount and location for placement of the acellular dermis was left to the discretion of the surgeon. All implants were placed in the subdermal tissues. MAIN OUTCOME MEASURES: The adequacy of acellular dermis for soft tissue augmentation was assessed by subjective evaluation of implant volume persistence, postoperative complications, and the restoration of normal contour. RESULTS: Of 10 patients who underwent implantation, 9 had no complications and 1 had a recurrent sterile abscess or mucocele at the implantation site. A 22-month postimplantation tissue sampling of acellular dermis in a patient with recurrent tumor revealed approximately 80% to 85% volume persistence. CONCLUSION: Preliminary experience with acellular dermis indicates that it shows promise in soft tissue augmentation.

Original languageEnglish
Pages (from-to)38-43
Number of pages6
JournalFacial Plastic Surgery and Aesthetic Medicine
Issue number1
StatePublished - 2001


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