Accumulation of globotriaosylceramide in a case of leiomyosarcoma

S. C. Li, S. K. Kundu, R. Degasperi, Y. T. Li

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Analysis of the glycosphingolipid composition in one case of uterine leiomyosarcoma metastasized to the liver showed an accumulation of globotriaosylceramide as compared with normal liver and uterus from which the tumour originated. The structure and the amount of glycosphingolipids were established by using specific glycosidases, permethylation analysis and h.p.l.c. The reason for the accumulation of globotriaosylceramide in leiomyosarcoma remains to be answered.

Original languageEnglish
Pages (from-to)925-927
Number of pages3
JournalBiochemical Journal
Volume240
Issue number3
DOIs
StatePublished - 1986
Externally publishedYes

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