Access and barriers to genomic classifiers for breast cancer and prostate cancer in India

Sruthi Ranganathan, Edward Christopher Dee, Neha Debnath, Tej A. Patel, Bhav Jain, Vedang Murthy

Research output: Contribution to journalReview articlepeer-review

Abstract

The incidence of cancer in general, including breast and prostate cancer specifically, is increasing in India. Breast and prostate cancers have genomic classifiers developed to guide therapy decisions. However, these genomic classifiers are often inaccessible in India due to high cost. These classifiers may also be less suitable to the Indian population, as data primarily from patients in wealthy Western countries were used in developing these genomic classifiers. In addition to the limitations in using these existing genomic classifiers, developing and validating new genomic classifiers for breast and prostate cancer in India is challenging due to the heterogeneity in the Indian population. However, there are steps that can be taken to address the various barriers that currently exist for accurate, accessible genomic classifiers for cancer in India.

Original languageEnglish
Pages (from-to)1335-1339
Number of pages5
JournalInternational Journal of Cancer
Volume154
Issue number8
DOIs
StateAccepted/In press - 2023

Keywords

  • India
  • cancer
  • disparities
  • genomic classifiers

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