Accelerator mass spectrometry for biomedical research

Karen Brown, Karen H. Dingley, Kenneth W. Turteltaub

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations

Abstract

Accelerator mass spectrometry (AMS) is the most sensitive method for detecting and quantifying rare long-lived isotopes with high precision. In this chapter, we review the principles underlying AMS-based biomedical studies, focusing on important practical considerations and experimental procedures needed for the detection and quantitation of 14C- and 3H-labeled compounds in various experiment types.

Original languageEnglish
Article number14
Pages (from-to)423-443
Number of pages21
JournalMethods in Enzymology
Volume402
DOIs
StatePublished - 2005
Externally publishedYes

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