Abuse of buprenorphine in the United States: 2003-2005

Meredith Y. Smith, J. Elise Bailey, George E. Woody, Herbert D. Kleber

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


This study examines trends in the reported abuse of two sublingual buprenorphine products, Subutex® and Suboxone®, in the United States. Quarterly counts of abuse cases were obtained from 18 regional poison control centers (PCCS) for 2003-2005. Seventy-seven abuse cases were reported, of which 7.8 percent involved Subutex® and 92.2 percent involved Suboxone®. The average quarterly ratio of abuse cases per 1,000 prescriptions dispensed was 0.08 (SD ± 0.09) for Subutex®, and 0.16 (SD ± 0.08) for Suboxone®. Findings suggest that these sublingual buprenorphine formulations have a low rate of abuse based on toxico-surveillance data.

Original languageEnglish
Pages (from-to)107-111
Number of pages5
JournalJournal of Addictive Diseases
Issue number3
StatePublished - 14 Aug 2007
Externally publishedYes


  • Buprenorphine-naloxone
  • Opioid analgesics
  • Opioid dependence
  • Prescription drug abuse
  • Sublingual buprenorphine
  • Suboxone®
  • Substitution therapy
  • Subutex®


Dive into the research topics of 'Abuse of buprenorphine in the United States: 2003-2005'. Together they form a unique fingerprint.

Cite this