Absorb bioresorbable vascular scaffold outcomes following implantation with routine intravascular imaging guidance

Costantino R. Costantini, Marcos A. Denk, Rafael M. De Macedo, Sergio G. Tarbine, Marcelo F. Santos, Marcio M. Luize, Joao C. Folador, Costantino O. Costantini, Gregg W. Stone

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objectives: We sought to describe the outcomes of BVS use from a single-center experience in which scaffold implantation was guided by intravascular imaging (ultrasound and/or optical coherence tomography) to identify and treat mechanical factors potentially related to BVS failure. Background: The Absorb bioresorbable vascular scaffold (BVS) has been associated with an unexpectedly high incidence of thrombosis. Methods: Between 11/2014 and 10/2016, 100 patients were treated with BVS. Intravascular imaging assessment before and after BVS implantation was performed in all cases. Results: Mean age was 58.1 years; 88% were male, 31% had diabetes, and 28% presented with acute coronary syndromes. A total of 171 lesions in 141 vessels were treated with 190 BVS (mean 1.9 scaffolds/patient). Further intervention following intravascular imaging to optimize BVS implantation was required in 31% of patients. Procedure success was 100%. All patients completed a 1-year follow-up. The 1-year rate of target lesion failure was 4%, and there were no cases (0%) of scaffold thrombosis, myocardial infarction, or death. Conclusions: In this real-world experience, the use of intravascular imaging to guide BVS implantation was associated with a high 1-year event-free survival rate, with no scaffold thrombosis.

Original languageEnglish
Pages (from-to)48-55
Number of pages8
JournalCatheterization and Cardiovascular Interventions
Volume97
Issue number1
DOIs
StatePublished - 1 Jan 2021
Externally publishedYes

Keywords

  • bioabsorbable implants
  • coronary thrombosis
  • intravascular imaging methods
  • percutaneous coronary revascularization

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