TY - JOUR

T1 - Absent relationship between the coil-embolization ratio in small aneurysms treated with a single detachable coil and outcomes

AU - Goddard, James K.

AU - Moran, Christopher J.

AU - Cross, De Witte T.

AU - Derdeyn, Colin P.

PY - 2005

Y1 - 2005

N2 - BACKGROUND AND PURPOSE: Although attenuated coil packing of intracranial aneurysms is an important goal of endovascular embolization, because of their small size, some aneurysms can only be treated with a single embolization coil. We retrospectively analyzed small aneurysms treated with a single Guglielmi detachable coil (GDC) to determine whether the coil-embolization ratio (CER) is predictive of embolization stability. METHODS: The CER was determined for 25 small (<7-mm diameter) intracranial aneurysms, each treated with a single embolization coil. The largest aneurysm dimension, estimated by comparison to anatomic landmarks, was used for volume calculation based on a spherical model. Coil volumes were according to manufacturer specifications. CER was calculated by the formula (coil volume/aneurysm volume) × 100%. Embolization stability was assessed by angiographic follow-up. RESULTS: The average CER for all aneurysms was 8.2% (SD, 6.5%; range, 0.6%-21.1%). Twelve percent of the aneurysms had a CER >20%. Follow-up angiographic assessment was conducted at an average of 30.8 months after initial treatment. Eighty-four percent of the aneurysms were obliterated. One large (6 × 10 mm) and 3 small (<1 mm) recurrences were identified. The average CER for unchanged aneurysms was 8.0% (SD, 5.9%) and for the recurrent aneurysms was 8.8% (SD, 8.7%), which was not statistically significant. CONCLUSION: Small aneurysms treated with a single coil achieved satisfactory stability despite having a low average packing attenuation. CER was not predictive of recurrence in small intracranial aneurysms treated with a single detachable coil.

AB - BACKGROUND AND PURPOSE: Although attenuated coil packing of intracranial aneurysms is an important goal of endovascular embolization, because of their small size, some aneurysms can only be treated with a single embolization coil. We retrospectively analyzed small aneurysms treated with a single Guglielmi detachable coil (GDC) to determine whether the coil-embolization ratio (CER) is predictive of embolization stability. METHODS: The CER was determined for 25 small (<7-mm diameter) intracranial aneurysms, each treated with a single embolization coil. The largest aneurysm dimension, estimated by comparison to anatomic landmarks, was used for volume calculation based on a spherical model. Coil volumes were according to manufacturer specifications. CER was calculated by the formula (coil volume/aneurysm volume) × 100%. Embolization stability was assessed by angiographic follow-up. RESULTS: The average CER for all aneurysms was 8.2% (SD, 6.5%; range, 0.6%-21.1%). Twelve percent of the aneurysms had a CER >20%. Follow-up angiographic assessment was conducted at an average of 30.8 months after initial treatment. Eighty-four percent of the aneurysms were obliterated. One large (6 × 10 mm) and 3 small (<1 mm) recurrences were identified. The average CER for unchanged aneurysms was 8.0% (SD, 5.9%) and for the recurrent aneurysms was 8.8% (SD, 8.7%), which was not statistically significant. CONCLUSION: Small aneurysms treated with a single coil achieved satisfactory stability despite having a low average packing attenuation. CER was not predictive of recurrence in small intracranial aneurysms treated with a single detachable coil.

UR - http://www.scopus.com/inward/record.url?scp=32944455860&partnerID=8YFLogxK

M3 - Article

C2 - 16155134

AN - SCOPUS:32944455860

SN - 0195-6108

VL - 26

SP - 1916

EP - 1920

JO - American Journal of Neuroradiology

JF - American Journal of Neuroradiology

IS - 8

ER -