Absence and atonic seizures induced by piperazine

David Yohai, Scott H. Barnett

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A previously healthy 2-year-old girl, who presented with transient neurologic dysfunction manifested mainly by absence and atonic seizures, was treated with large doses of the antihelminthic piperazine hexahydrate. The role of piperazine salts and piperazine-containing compounds in producing neurotoxic side effects is discussed. We suggest that these drugs be considered as a possible cause of transient encephalopathy and nonepileptic seizures in previously healthy individuals.

Original languageEnglish
Pages (from-to)393-394
Number of pages2
JournalPediatric Neurology
Issue number6
StatePublished - 1989
Externally publishedYes


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