TY - JOUR
T1 - Abnormal karyotype of fetuses with omphalocele
T2 - Prediction based on omphalocele contents
AU - Benacerraf, Beryl R.
AU - Saltzman, Daniel H.
AU - Estroff, Judith A.
AU - Frigoletto, Fredric D.
PY - 1990/3
Y1 - 1990/3
N2 - The majority of fetuses with omphalocele have other congenital abnormalities and, in many cases, an abnormal karyotype. We retrospectively studied 22 consecutive fetuses with sonographically diagnosed omphalocele and available karyotype to determine whether the contents of the omphalocele could predict the karyotype. of these 22 fetuses, 18 had normal and four had abnormal karyotypes. Sixteen of the karyotypically normal fetuses had liver herniated into the omphalocele and two had only bowel present in the defect. All four of the fetuses with abnormal chromosomes had only bowel in the defect.
AB - The majority of fetuses with omphalocele have other congenital abnormalities and, in many cases, an abnormal karyotype. We retrospectively studied 22 consecutive fetuses with sonographically diagnosed omphalocele and available karyotype to determine whether the contents of the omphalocele could predict the karyotype. of these 22 fetuses, 18 had normal and four had abnormal karyotypes. Sixteen of the karyotypically normal fetuses had liver herniated into the omphalocele and two had only bowel present in the defect. All four of the fetuses with abnormal chromosomes had only bowel in the defect.
UR - http://www.scopus.com/inward/record.url?scp=0025191352&partnerID=8YFLogxK
M3 - Article
C2 - 2304703
AN - SCOPUS:0025191352
SN - 0029-7844
VL - 75
SP - 317
EP - 319
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
IS - 3
ER -