A wake-up call: We need phage therapy now

Karin Moelling, Felix Broecker, Christian Willy

Research output: Contribution to journalReview articlepeer-review

85 Scopus citations

Abstract

The rise of multidrug-resistant bacteria has resulted in an increased interest in phage therapy, which historically preceded antibiotic treatment against bacterial infections. To date, there have been no reports of serious adverse events caused by phages. They have been successfully used to cure human diseases in Eastern Europe for many decades. More recently, clinical trials and case reports for a variety of indications have shown promising results. However, major hurdles to the introduction of phage therapy in the Western world are the regulatory and legal frameworks. Present regulations may take a decade or longer to be fulfilled. It is of urgent need to speed up the availability of phage therapy.

Original languageEnglish
Article number688
JournalViruses
Volume10
Issue number12
DOIs
StatePublished - Dec 2018

Keywords

  • Helsinki declaration
  • Magistral preparation
  • Phage therapy
  • Phages
  • Regulation

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