A Val193Met mutation in GPIIIa results in a GPIIb/IIIa receptor with a constitutively high affinity for a small ligand

Keyphrases

• 3' End 16%
• Adhesion 16%
• Binding Affinity 16%
• Bleeding Time 16%
• Compound Heterozygous mutation 16%
• Dithiothreitol 33%
• Exon 3 16%
• Fibrinogen 16%
• Fibrinogen Binding 16%
• Genetic Analysis 16%
• Glanzmann Thrombasthenia 16%
• Glycoprotein IIb/IIIa Receptor 16%
• GPIIbIIIa 100%
• GPIIIa 100%
• HEK293 Cells 16%
• High Affinity 100%
• Nonapeptides 16%
• Platelet Adhesion 16%
• Platelet Aggregation 33%
• Platelets 100%
• Premature Stop Codon 16%
• Prolonged Bleeding 16%
• RGD Mimetics 16%
• Small Molecule Ligands 100%
• Solid Phase 16%

Biochemistry, Genetics and Molecular Biology

• Adenosine Diphosphate 20%
• Allele 40%
• Binding Affinity 20%
• Bleeding Time 20%
• Dithiothreitol 40%
• Eicosanoid Receptor 100%
• Exon 20%
• Fibrinogen 40%
• Genetic Carrier 20%
• Genetics 20%
• Glanzmann's Thrombasthenia 20%
• Glycoprotein IIb/IIIa 20%
• Heterozygote 20%
• Platelet 100%
• Solid 20%
• Stop Codon 20%
• Thrombocyte Adhesion 20%
• Thrombocyte Aggregation 40%
• Thrombocyte Membrane 20%
• Wild Type 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Adenosine Diphosphate 50%
• Bleeding 50%
• Dithiothreitol 100%
• Fibrinogen 100%
• Fibrinogen Receptor 50%
• Glanzmann Disease 50%
• Prematurity 50%
• Receptor 100%