A two-step approach for feature selection and classifier ensemble construction in computer-aided diagnosis

Michael C. Lee, Lilla Boroczky, Kivilcim Sungur-Stasik, Aaron D. Cann, Alain C. Borczuk, Steven M. Kawut, Charles A. Powell

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

17 Scopus citations

Abstract

Accurate classification methods are critical in computer-aided diagnosis and other clinical decision support systems. Previous research has studied methods for combining genetic algorithms for feature selection with ensemble classifier systems in an effort to increase classification accuracy. We propose a two-step approach that first uses genetic algorithms to reduce the number of features used to characterize the data, then applies the random subspace method on the remaining features to create a set of diverse but high performing classifiers. These classifiers are combined using ensemble learning techniques to yield afinal classification. We demonstrate this approach for computer-aided diagnosis of solitary pulmonary nodules from CT scans, in which the proposed method outperforms several previously described methods.

Original languageEnglish
Title of host publicationProceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems, CBMS 2008
Pages548-553
Number of pages6
DOIs
StatePublished - 2008
Externally publishedYes
Event21st IEEE International Symposium on Computer-Based Medical Systems, CBMS 2008 - Jyvaskyla, Finland
Duration: 17 Jun 200819 Jun 2008

Publication series

NameProceedings - IEEE Symposium on Computer-Based Medical Systems
ISSN (Print)1063-7125

Conference

Conference21st IEEE International Symposium on Computer-Based Medical Systems, CBMS 2008
Country/TerritoryFinland
CityJyvaskyla
Period17/06/0819/06/08

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