A Study of Neomycin Instillation into Orthopedic Surgical Wounds

Benjamin A. Nachamie; Robert S. Siffert; Morton S. Bryer

doi:10.1001/jama.1968.03140210041010

A Study of Neomycin Instillation into Orthopedic Surgical Wounds

Benjamin A. Nachamie, Robert S. Siffert, Morton S. Bryer

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

The use of parenterally administered antibiotics preoperatively and postoperatively in orthopedic procedures has not proved significantly effective in preventing postoperative infection. This present controlled study (466 patients in a 28-month period) investigated the effect of local neomycin sulfate irrigation of orthopedic surgical wounds before closure on postoperative wound healing and complications. By the technique of irrigation and the doses of neomycin sulfate instilled into the wound (100 cc of 0.1% solution), there was no evidence that the antibiotic significantly altered the rate of infection or wound healing in osseous or soft tissue orthopedic wounds with or without metal implants.

Original language	English
Pages (from-to)	687-689
Number of pages	3
Journal	JAMA - Journal of the American Medical Association
Volume	204
Issue number	8
DOIs	https://doi.org/10.1001/jama.1968.03140210041010
State	Published - 20 May 1968

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A Study of Neomycin Instillation into Orthopedic Surgical Wounds

Abstract

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