A simple colorimetric urine test for pheochromocytoma

Stanley E. Gitlow, Leonard Ornstein, Milton Mendlowitz, Sarah Khassis, Elizabeth Kruk

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


A rapid and simple chemical technic for screening hypertensive subjects for the presence of a pheochromocytoma is described. The procedure involves the semiquantitative estimation of urinary 3-methoxy, 4-hydroxymandelic acid (VMA). This test differentiates between normal subjects or patients with primary hypertension and patients with pheochromocytoma. A negative result requires no further study whereas a positive one necessitates confirmation by Chromatographic determination of VMA.

Original languageEnglish
Pages (from-to)921-926
Number of pages6
JournalAmerican Journal of Medicine
Issue number6
StatePublished - Jun 1960


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