A shielded synthesis system for production of 2-deoxy-2-[ 18F]fluoro-D-glucose

J. S. Fowler, R. R. MacGregor, A. P. Wolf, A. A. Farrell, K. I. Karlstrom, T. J. Ruth

Research output: Contribution to journalArticlepeer-review

68 Scopus citations


A remotely operated, shielded synthesis system for the production of 2-deoxy-2-[ 18F]fluoro-D-glucose ( 18FDG) for clinical studies has been developed. Using this system, 25 mCi of 18FDG are produced at the end of a 60-min synthesis from ~300 mCi of F-18 (total F-18 among various components of the synthesis system has been measured. This yield of 18FDG (25 mCi) is ample for two consecutive human studies in house or for shipment to collaborating institutions within a 3-hr (door to door) radius.

Original languageEnglish
Pages (from-to)376-380
Number of pages5
JournalJournal of Nuclear Medicine
Issue number4
StatePublished - 1981
Externally publishedYes


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