A scaleable formal total synthesis of dehydrogliotoxin

Travis C. McMahon; Sarah Stanley; Edward Kazyanskaya; Deborah Hung; John L. Wood

doi:10.1016/j.tetlet.2011.01.138

A scaleable formal total synthesis of dehydrogliotoxin

Travis C. McMahon
, Sarah Stanley
, Edward Kazyanskaya
, Deborah Hung
, John L. Wood

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A formal total synthesis of the epidithiodiketopiperazine natural product, dehydrogliotoxin (2), utilizing an intramolecular ring closure to form key intermediate 5 is described.

Original language	English
Pages (from-to)	2262-2264
Number of pages	3
Journal	Tetrahedron Letters
Volume	52
Issue number	17
DOIs	https://doi.org/10.1016/j.tetlet.2011.01.138
State	Published - 27 Apr 2011
Externally published	Yes

Keywords

Dehydrogliotoxin
Diketopiperazine
Formal synthesis
Gliotoxin

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10.1016/j.tetlet.2011.01.138

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@article{b753eb7b0bf54db4b53aec334a85c784,

title = "A scaleable formal total synthesis of dehydrogliotoxin",

abstract = "A formal total synthesis of the epidithiodiketopiperazine natural product, dehydrogliotoxin (2), utilizing an intramolecular ring closure to form key intermediate 5 is described.",

keywords = "Dehydrogliotoxin, Diketopiperazine, Formal synthesis, Gliotoxin",

author = "McMahon, \{Travis C.\} and Sarah Stanley and Edward Kazyanskaya and Deborah Hung and Wood, \{John L.\}",

year = "2011",

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day = "27",

doi = "10.1016/j.tetlet.2011.01.138",

language = "English",

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journal = "Tetrahedron Letters",

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number = "17",

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TY - JOUR

T1 - A scaleable formal total synthesis of dehydrogliotoxin

AU - McMahon, Travis C.

AU - Stanley, Sarah

AU - Kazyanskaya, Edward

AU - Hung, Deborah

AU - Wood, John L.

PY - 2011/4/27

Y1 - 2011/4/27

N2 - A formal total synthesis of the epidithiodiketopiperazine natural product, dehydrogliotoxin (2), utilizing an intramolecular ring closure to form key intermediate 5 is described.

AB - A formal total synthesis of the epidithiodiketopiperazine natural product, dehydrogliotoxin (2), utilizing an intramolecular ring closure to form key intermediate 5 is described.

KW - Dehydrogliotoxin

KW - Diketopiperazine

KW - Formal synthesis

KW - Gliotoxin

UR - https://www.scopus.com/pages/publications/79953179623

U2 - 10.1016/j.tetlet.2011.01.138

DO - 10.1016/j.tetlet.2011.01.138

M3 - Article

AN - SCOPUS:79953179623

SN - 0040-4039

VL - 52

SP - 2262

EP - 2264

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 17

ER -

A scaleable formal total synthesis of dehydrogliotoxin

Abstract

Keywords

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