A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection

Phanichand Kodali; Julio A. Landero-Figueroa; Joseph Caruso; Opeolu Adeoye

doi:10.1007/s00702-013-1018-9

A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection

Phanichand Kodali, Julio A. Landero-Figueroa, Joseph Caruso, Opeolu Adeoye

Research output: Contribution to journal › Article › peer-review

Abstract

Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.

Original language	English
Pages (from-to)	1441-1445
Number of pages	5
Journal	Journal of Neural Transmission
Volume	120
Issue number	10
DOIs	https://doi.org/10.1007/s00702-013-1018-9
State	Published - Oct 2013
Externally published	Yes

Keywords

Biomarkers
Blood plasma
HPLC
Stroke

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10.1007/s00702-013-1018-9

Cite this

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abstract = "Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.",

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AU - Kodali, Phanichand

AU - Landero-Figueroa, Julio A.

AU - Caruso, Joseph

AU - Adeoye, Opeolu

PY - 2013/10

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AB - Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.

KW - Biomarkers

KW - Blood plasma

KW - HPLC

KW - Stroke

UR - https://www.scopus.com/pages/publications/84885421341

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DO - 10.1007/s00702-013-1018-9

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A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection

Abstract

Keywords

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