A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection

Phanichand Kodali, Julio A. Landero-Figueroa, Joseph Caruso, Opeolu Adeoye

Research output: Contribution to journalArticlepeer-review

Abstract

Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.

Original languageEnglish
Pages (from-to)1441-1445
Number of pages5
JournalJournal of Neural Transmission
Volume120
Issue number10
DOIs
StatePublished - Oct 2013
Externally publishedYes

Keywords

  • Biomarkers
  • Blood plasma
  • HPLC
  • Stroke

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