TY - JOUR
T1 - A practical approach to the diagnosis and treatment of vitiligo in children
AU - Ezzedine, Khaled
AU - Silverberg, Nanette
N1 - Publisher Copyright:
© 2016 by the American Academy of Pediatrics.
PY - 2016/7
Y1 - 2016/7
N2 - Vitiligo is a common inflammatory skin disease with a worldwide prevalence of 0.5% to 2.0% of the population. In the pediatric population, the exact prevalence of vitiligo is unknown, although many studies state that most cases of vitiligo are acquired early in life. The disease is disfiguring, with a major psychological impact on children and their parents. Half of vitiligo cases have a childhood onset, needing thus a treatment approach that will minimize treatment side effects while avoiding psychological impacts. Management of vitiligo should take into account several factors, including extension, psychological impact, and possible associations with other autoimmune diseases. This review discusses the epidemiology of vitiligo and outlines the various clinical presentations associated with the disorder and their differential diagnosis. In addition, the pathophysiology and genetic determinants, the psychological impact of vitiligo, and management strategies are reviewed.
AB - Vitiligo is a common inflammatory skin disease with a worldwide prevalence of 0.5% to 2.0% of the population. In the pediatric population, the exact prevalence of vitiligo is unknown, although many studies state that most cases of vitiligo are acquired early in life. The disease is disfiguring, with a major psychological impact on children and their parents. Half of vitiligo cases have a childhood onset, needing thus a treatment approach that will minimize treatment side effects while avoiding psychological impacts. Management of vitiligo should take into account several factors, including extension, psychological impact, and possible associations with other autoimmune diseases. This review discusses the epidemiology of vitiligo and outlines the various clinical presentations associated with the disorder and their differential diagnosis. In addition, the pathophysiology and genetic determinants, the psychological impact of vitiligo, and management strategies are reviewed.
UR - http://www.scopus.com/inward/record.url?scp=84976907924&partnerID=8YFLogxK
U2 - 10.1542/peds.2015-4126
DO - 10.1542/peds.2015-4126
M3 - Review article
C2 - 27328922
AN - SCOPUS:84976907924
SN - 0031-4005
VL - 138
JO - Pediatrics
JF - Pediatrics
IS - 1
M1 - e20154126
ER -