A practical approach to the diagnosis and treatment of vitiligo in children

Khaled Ezzedine, Nanette Silverberg

Research output: Contribution to journalReview articlepeer-review

55 Scopus citations

Abstract

Vitiligo is a common inflammatory skin disease with a worldwide prevalence of 0.5% to 2.0% of the population. In the pediatric population, the exact prevalence of vitiligo is unknown, although many studies state that most cases of vitiligo are acquired early in life. The disease is disfiguring, with a major psychological impact on children and their parents. Half of vitiligo cases have a childhood onset, needing thus a treatment approach that will minimize treatment side effects while avoiding psychological impacts. Management of vitiligo should take into account several factors, including extension, psychological impact, and possible associations with other autoimmune diseases. This review discusses the epidemiology of vitiligo and outlines the various clinical presentations associated with the disorder and their differential diagnosis. In addition, the pathophysiology and genetic determinants, the psychological impact of vitiligo, and management strategies are reviewed.

Original languageEnglish
Article numbere20154126
JournalPediatrics
Volume138
Issue number1
DOIs
StatePublished - Jul 2016
Externally publishedYes

Fingerprint

Dive into the research topics of 'A practical approach to the diagnosis and treatment of vitiligo in children'. Together they form a unique fingerprint.

Cite this