TY - JOUR
T1 - A placebo controlled trial for an NMO relapse prevention treatment
T2 - Ethical considerations
AU - Rhodes, Rosamond
N1 - Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2015/11
Y1 - 2015/11
N2 - This paper addresses the ethical acceptability of a proposed placebo controlled trial of a new intervention as a possible relapse prevention treatment for Neuromyelitis Optica (NMO). In the analysis of this controversial ethical issue, the author points out significant factors that are often overlooked or ignored, such as the life-long implications for study participants and others living with the disease, and also addresses commonly noted issues, such as vulnerability, benefits, harms, and justice that always require attention in research review.
AB - This paper addresses the ethical acceptability of a proposed placebo controlled trial of a new intervention as a possible relapse prevention treatment for Neuromyelitis Optica (NMO). In the analysis of this controversial ethical issue, the author points out significant factors that are often overlooked or ignored, such as the life-long implications for study participants and others living with the disease, and also addresses commonly noted issues, such as vulnerability, benefits, harms, and justice that always require attention in research review.
KW - Evidence
KW - Justice
KW - NMO
KW - Placebo controlled trial
KW - Research ethics
UR - https://www.scopus.com/pages/publications/84947569927
U2 - 10.1016/j.msard.2015.07.018
DO - 10.1016/j.msard.2015.07.018
M3 - Article
C2 - 26590665
AN - SCOPUS:84947569927
SN - 2211-0348
VL - 4
SP - 580
EP - 584
JO - Multiple Sclerosis and Related Disorders
JF - Multiple Sclerosis and Related Disorders
IS - 6
ER -