A placebo controlled trial for an NMO relapse prevention treatment: Ethical considerations

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Abstract

This paper addresses the ethical acceptability of a proposed placebo controlled trial of a new intervention as a possible relapse prevention treatment for Neuromyelitis Optica (NMO). In the analysis of this controversial ethical issue, the author points out significant factors that are often overlooked or ignored, such as the life-long implications for study participants and others living with the disease, and also addresses commonly noted issues, such as vulnerability, benefits, harms, and justice that always require attention in research review.

Original languageEnglish
Pages (from-to)580-584
Number of pages5
JournalMultiple Sclerosis and Related Disorders
Volume4
Issue number6
DOIs
StatePublished - Nov 2015

Keywords

  • Evidence
  • Justice
  • NMO
  • Placebo controlled trial
  • Research ethics

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