A parametric fitting algorithm for segmentation of cell images

Hai Shan Wu, Joseph Barba, Joan Gil

Research output: Contribution to journalArticlepeer-review

106 Scopus citations

Abstract

This paper presents a parametric fitting algorithm for segmentation of cervical and breast cells images from cytology smears. A parametric elliptical model for cells is introduced and the parameters adjusted to fit the cell shapes while minimizing a cost function. Segmentation results of noisy human cervical cell and textured breast cell images demonstrate that the proposed parametric fitting algorithm is very successful in segmentation of images of both nonoverlapped and overlapped elliptically shaped cells.

Original languageEnglish
Pages (from-to)400-407
Number of pages8
JournalIEEE Transactions on Biomedical Engineering
Volume45
Issue number3
DOIs
StatePublished - Mar 1998
Externally publishedYes

Keywords

  • Biomedical image processing
  • Cell images
  • Quantitative pathology
  • Segmentation

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