A novel method to deliver the filtrap coronary embolic protection filter using a manual thrombectomy catheter: In vitro and in vivo comparison with the conventional method

Shin Watanabe, Naritatsu Saito, Akihiro Tokushige, Bao Bingyuan, Yoshiaki Kawase, Takeshi Kimura

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Although several types of distal embolic protection devices have been developed, they are usually difficult to use because of their stiff and bulky characteristics. We present a novel method to deliver the coronary embolic protection filter via a manual thrombectomy catheter. Methods: We modified the Filtrap embolic protection filter (Nipro Corporation) to pass through the aspiration thrombectomy catheter. Three interventional cardiologists performed the Filtrap delivery with in vivo and in vitro coronary arteries using two different methods. The in vitro experiments were performed using a Circuit Cardiac Catheterization Simulator (Just Medical Corporation) with and without coronary artery stenosis. The in vivo experiment was performed using a normal pig coronary artery. The times required for Filtrap delivery in the two different methods were compared. The target lesions were the main and side branch of the left anterior descending, left circumflex, and right coronary arteries. Results: The average Filtrap delivery time when using the thrombectomy catheter was significantly shorter compared to the time using the conventional method (in vitro experiment without coronary stenosis, 39 ± 14 seconds vs 30 ± 6 seconds and P=.019; in vitro experiment with multiple coronary stenosis, 69 ± 55 seconds vs 32 ± 11 seconds and P=.012; in vivo experiment, 169 ± 166 seconds vs 51 ± 12 seconds; P=.019). Conclusion: The study results indicate that delivery of the coronary embolic protection filter via a manual thrombectomy catheter may simplify the procedure and decrease the procedure time.

Original languageEnglish
Pages (from-to)159-163
Number of pages5
JournalJournal of Invasive Cardiology
Volume24
Issue number4
StatePublished - Apr 2012
Externally publishedYes

Keywords

  • Filtrap device
  • embolic protection filter devices

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