A novel descriptor for protein similarity analysis

Ping An He, Xiao Fang Li, Jia Liang Yang, Jun Wang

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Based on three kinds of indices of physicochemical properties on amino acids, a 3D graphical representation of protein sequences is introduced. Then, we present a graph matrix representation called the 2-order difference matrix to characterize the 3D graphical representation. Using this 2-order difference matrix, we propose an efficient method to compare protein sequences. Finally, an example is shown to compare the NADH dehydrogenase subunit 5 (ND5) protein sequences of 9 species.

Original languageEnglish
Pages (from-to)445-458
Number of pages14
JournalMatch
Volume65
Issue number2
StatePublished - 2011
Externally publishedYes

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