A Novel Algorithm for the Management of Inpatient COVID-19 Glucocorticoid-Induced Hyperglycemia

Alexander B. Karol; Natalia Viera; Selassie J. Ogyaadu; Danielle Brooks; Nirali A. Shah; Anne S. Linker; David W. Lam; Carol J. Levy; Grenye O’Malley

doi:10.2337/cd22-0083

A Novel Algorithm for the Management of Inpatient COVID-19 Glucocorticoid-Induced Hyperglycemia

Alexander B. Karol, Natalia Viera, Selassie J. Ogyaadu, Danielle Brooks, Nirali A. Shah, Anne S. Linker, David W. Lam, Carol J. Levy, Grenye O’Malley

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Hyperglycemia in hospitalized patients with coronavirus disease 2019 (COVID-19) is linked to increased morbidity and mortality. This article reports on a novel insulin titration protocol for the management of glucocorticoid-induced hyperglycemia in hospitalized patients with COVID-19. Sixty-five patients with COVID-19 and glucocorticoid-induced hyperglycemia admitted after the protocol implementation were matched 1:1 to patients admitted before the treatment protocol rollout for analysis. In a large, diverse health system, the protocol achieved reductions in hypoglycemic events without increasing hyperglycemia or insulin use.

Original language	English
Pages (from-to)	378-385
Number of pages	8
Journal	Clinical Diabetes
Volume	41
Issue number	3
DOIs	https://doi.org/10.2337/cd22-0083
State	Published - Jul 2023

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title = "A Novel Algorithm for the Management of Inpatient COVID-19 Glucocorticoid-Induced Hyperglycemia",

abstract = "Hyperglycemia in hospitalized patients with coronavirus disease 2019 (COVID-19) is linked to increased morbidity and mortality. This article reports on a novel insulin titration protocol for the management of glucocorticoid-induced hyperglycemia in hospitalized patients with COVID-19. Sixty-five patients with COVID-19 and glucocorticoid-induced hyperglycemia admitted after the protocol implementation were matched 1:1 to patients admitted before the treatment protocol rollout for analysis. In a large, diverse health system, the protocol achieved reductions in hypoglycemic events without increasing hyperglycemia or insulin use.",

author = "Karol, {Alexander B.} and Natalia Viera and Ogyaadu, {Selassie J.} and Danielle Brooks and Shah, {Nirali A.} and Linker, {Anne S.} and Lam, {David W.} and Levy, {Carol J.} and Grenye O{\textquoteright}Malley",

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AU - Karol, Alexander B.

AU - Viera, Natalia

AU - Ogyaadu, Selassie J.

AU - Brooks, Danielle

AU - Shah, Nirali A.

AU - Linker, Anne S.

AU - Lam, David W.

AU - Levy, Carol J.

AU - O’Malley, Grenye

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N2 - Hyperglycemia in hospitalized patients with coronavirus disease 2019 (COVID-19) is linked to increased morbidity and mortality. This article reports on a novel insulin titration protocol for the management of glucocorticoid-induced hyperglycemia in hospitalized patients with COVID-19. Sixty-five patients with COVID-19 and glucocorticoid-induced hyperglycemia admitted after the protocol implementation were matched 1:1 to patients admitted before the treatment protocol rollout for analysis. In a large, diverse health system, the protocol achieved reductions in hypoglycemic events without increasing hyperglycemia or insulin use.

AB - Hyperglycemia in hospitalized patients with coronavirus disease 2019 (COVID-19) is linked to increased morbidity and mortality. This article reports on a novel insulin titration protocol for the management of glucocorticoid-induced hyperglycemia in hospitalized patients with COVID-19. Sixty-five patients with COVID-19 and glucocorticoid-induced hyperglycemia admitted after the protocol implementation were matched 1:1 to patients admitted before the treatment protocol rollout for analysis. In a large, diverse health system, the protocol achieved reductions in hypoglycemic events without increasing hyperglycemia or insulin use.

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A Novel Algorithm for the Management of Inpatient COVID-19 Glucocorticoid-Induced Hyperglycemia

Abstract

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