A Noninvasive LSO-APD Blood Radioactivity Monitor for PET Imaging Studies

Sepideh Shokouhi; Sean P. Stoll; Azael Villanueva; Paul Vaska; David J. Schlyer; Craig L. Woody; Bo Yu; Paul O'Connor; Jean Francois Pratte; Veljko Radeka; Nora Volkow; Joanna S. Fowler

doi:10.1109/TNS.2003.817284

A Noninvasive LSO-APD Blood Radioactivity Monitor for PET Imaging Studies

Sepideh Shokouhi, Sean P. Stoll, Azael Villanueva, Paul Vaska, David J. Schlyer, Craig L. Woody, Bo Yu, Paul O'Connor, Jean Francois Pratte, Veljko Radeka, Nora Volkow, Joanna S. Fowler

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A study has been carried out to investigate the possibility of using a pair of LSO + APD detector arrays to obtain a noninvasive measurement of the arterial input function for use in PET. The main focus of this study was to determine the spatial resolution and sensitivity required to obtain a high quality image that would permit a precise determination of the region of interest around the wrist artery. From these data a quantitative arterial input function that has minimal interference from the tissue and vein background can be obtained. The detector arrays were operated in coincidence counting mode to obtain planar images of various phantoms to demonstrate the feasibility of the concept.

Original language	English
Pages (from-to)	1457-1461
Number of pages	5
Journal	IEEE Transactions on Nuclear Science
Volume	50
Issue number	5 II
DOIs	https://doi.org/10.1109/TNS.2003.817284
State	Published - Oct 2003
Externally published	Yes

Keywords

Blood monitor
Input function
Modeling
Radiation detector

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10.1109/TNS.2003.817284

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title = "A Noninvasive LSO-APD Blood Radioactivity Monitor for PET Imaging Studies",

abstract = "A study has been carried out to investigate the possibility of using a pair of LSO + APD detector arrays to obtain a noninvasive measurement of the arterial input function for use in PET. The main focus of this study was to determine the spatial resolution and sensitivity required to obtain a high quality image that would permit a precise determination of the region of interest around the wrist artery. From these data a quantitative arterial input function that has minimal interference from the tissue and vein background can be obtained. The detector arrays were operated in coincidence counting mode to obtain planar images of various phantoms to demonstrate the feasibility of the concept.",

keywords = "Blood monitor, Input function, Modeling, Radiation detector",

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language = "English",

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AU - Shokouhi, Sepideh

AU - Stoll, Sean P.

AU - Villanueva, Azael

AU - Vaska, Paul

AU - Schlyer, David J.

AU - Woody, Craig L.

AU - Yu, Bo

AU - O'Connor, Paul

AU - Pratte, Jean Francois

AU - Radeka, Veljko

AU - Volkow, Nora

AU - Fowler, Joanna S.

PY - 2003/10

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N2 - A study has been carried out to investigate the possibility of using a pair of LSO + APD detector arrays to obtain a noninvasive measurement of the arterial input function for use in PET. The main focus of this study was to determine the spatial resolution and sensitivity required to obtain a high quality image that would permit a precise determination of the region of interest around the wrist artery. From these data a quantitative arterial input function that has minimal interference from the tissue and vein background can be obtained. The detector arrays were operated in coincidence counting mode to obtain planar images of various phantoms to demonstrate the feasibility of the concept.

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KW - Blood monitor

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KW - Modeling

KW - Radiation detector

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A Noninvasive LSO-APD Blood Radioactivity Monitor for PET Imaging Studies

Abstract

Keywords

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