A new system to supply carbon dioxide safely to glaucoma patients

Yoshiaki Niwa, Alon Harris, Larry Kagemann, Tetsuya Yamamoto, Masayuki Matsubara, Daisuke Takahashi, Yoshiaki Kitazawa

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Purpose: To develop a new system for safely supplying carbon dioxide (CO2) to open-angle glaucoma patients. Methods: The orbital hemodynamics of 7 glaucoma patients were determined by color Doppler imaging under baseline conditions and during CO2 supplementation sufficient to increase the end- tidal CO2 partial pressure by 10%. Systemic conditions, including oxygen saturation and blood pressure, were monitored throughout the CO2 inhalation. Results: Our results demonstrate that this new system enables us to supply CO2 in a safe, controlled manner to glaucoma patients. Conclusions: This new system will be useful for investigating the effects of vasodilation by CO2 on orbital blood flow.

Original languageEnglish
Pages (from-to)16-19
Number of pages4
JournalJapanese Journal of Ophthalmology
Issue number1
StatePublished - Jan 1999
Externally publishedYes


  • Carbon dioxide
  • Color Doppler imaging
  • Glaucoma


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