Purpose: To develop a new system for safely supplying carbon dioxide (CO2) to open-angle glaucoma patients. Methods: The orbital hemodynamics of 7 glaucoma patients were determined by color Doppler imaging under baseline conditions and during CO2 supplementation sufficient to increase the end- tidal CO2 partial pressure by 10%. Systemic conditions, including oxygen saturation and blood pressure, were monitored throughout the CO2 inhalation. Results: Our results demonstrate that this new system enables us to supply CO2 in a safe, controlled manner to glaucoma patients. Conclusions: This new system will be useful for investigating the effects of vasodilation by CO2 on orbital blood flow.
- Carbon dioxide
- Color Doppler imaging