Abstract

The generation of planar cell polarity (PCP) and tissue shape during morphogenesis is tightly linked, but it is not clear how. Aigouy et al. (2010) now show in the developing Drosophila wing that PCP initially has a radial orientation that becomes realigned to the proximal-distal axis of organ shape by mechanical forces and cell rearrangements mediated by Dachsous.

Original languageEnglish
Pages (from-to)674-676
Number of pages3
JournalCell
Volume142
Issue number5
DOIs
StatePublished - 3 Sep 2010

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