A New Function for p53 Ubiquitination

Yuko Hirano, Ze'ev Ronai

Research output: Contribution to journalShort surveypeer-review

11 Scopus citations

Abstract

The amount of p53 protein in a cell is normally limited by ubiquitin-dependent degradation. In this issue of Cell, Le Cam et al. (2006) reveal that p53 ubiquitination contributes to transcriptional activation rather than protein stability. These results may provide insight into how p53 can modulate diverse cellular processes such as growth arrest and apoptosis.

Original languageEnglish
Pages (from-to)675-677
Number of pages3
JournalCell
Volume127
Issue number4
DOIs
StatePublished - 17 Nov 2006
Externally publishedYes

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