A new approach in the management of chronic nonhealing leg ulcers

Alan A. Saber, Kareem Z. Yahya, Arun Rao, Michael Castellano, Michael Cioroiu, Robert Grossi, Robert M. Tornambe

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Chronic leg ulcers are a major cause of mortality and morbidity. The efficacy of hyperbaric oxygen treatment is being evaluated in the management of nonhealing leg ulcers to improve skin graft survival. Twenty-seven patients with 36 chronic leg ulcers were examined. Each wound received 12 preoperative hyperbaric oxygen treatments, split-thickness skin grafting, followed by 12 postoperative hyperbaric oxygen treatments. Wound transcutaneous oxygen tension measurements (TCOM) were taken. The graft take was evaluated. At 18 months follow-up, 18 skin grafts (50%) showed complete take, 15 (41.7%) demonstrated partial take, and 3 (8.3%) failed. Hyperbaric oxygen treatment is an effective adjunct in the management of chronic leg ulcers, and its use resulted in increased graft take and survival.

Original languageEnglish
Pages (from-to)321-323
Number of pages3
JournalJournal of Investigative Surgery
Issue number6
StatePublished - Nov 2005


  • Hyperbaric oxygen treatment
  • Nonhealing leg ulcers
  • Skin graft


Dive into the research topics of 'A new approach in the management of chronic nonhealing leg ulcers'. Together they form a unique fingerprint.

Cite this