A modern definition of mediastinal compartments

Brett W. Carter, Noriyuki Tomiyama, Faiz Y. Bhora, Melissa L.Rosado De Christenson, Jun Nakajima, Phillip M. Boiselle, Frank C. Detterbeck, Edith M. Marom

Research output: Contribution to journalArticlepeer-review

100 Scopus citations


Division of the mediastinum into compartments is used to help narrow the differential diagnosis of newly detected mediastinal masses, to assist in planning biopsy and surgical procedures, and to facilitate communication among clinicians of multiple disciplines. Several traditional mediastinal division schemes exist based upon arbitrary landmarks on the lateral chest radiograph. We describe a modern, computed tomography-based mediastinal division scheme, which has been accepted by the International Thymic Malignancy Interest Group as a new standard. This clinical classification defines a prevascular (anterior), a visceral (middle), and a paravertebral (posterior) compartment, with anatomic boundaries defined clearly by computed tomography. It is our intention that this definition be used in the reporting of clinical cases and the design of prospective clinical trials.

Original languageEnglish
Pages (from-to)S97-S101
JournalJournal of Thoracic Oncology
Issue number9
StatePublished - Sep 2014
Externally publishedYes


  • CT
  • Compartments
  • Mediastinum


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