A model-fitting implementation of the DeFries-Fulker model for selected twin data

S. Purcell, P. C. Sham

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

In this research note, DeFries-Fulker (DF) regression analysis is reframed in model-fitting terms, where an individual's expected score is modeled as a function of their co-twin's proband status. This more flexible implementation of the DF model allows DZ-O twins to be incorporated in a sex-limitation model. Brief simulation results are presented along with the Mx scripts used.

Original languageEnglish
Pages (from-to)271-278
Number of pages8
JournalBehavior Genetics
Volume33
Issue number3
DOIs
StatePublished - May 2003
Externally publishedYes

Keywords

  • DeFries-Fulker analysis
  • Maximum likelihood estimation
  • Sex differences
  • Twins

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