A methylation clock model of mild SARS-CoV-2 infection provides insight into immune dysregulation

Keyphrases

• SARS-CoV-2 Infection 100%
• Immune Dysregulation 100%
• DNA Methylation Clock 100%
• Clock Model 100%
• Methylation 66%
• Older Adults 66%
• Post-infection 66%
• Mildly Symptomatic 66%
• Virus 33%
• DNA Methylation (DNAm) 33%
• Inflammatory Diseases 33%
• Autoimmune Disease 33%
• Differentially Methylated Regions 33%
• Machine Learning Models 33%
• Asymptomatic Infection 33%
• Differential Gene Expression 33%
• Epigenetic Landscape 33%
• Diverse Populations 33%
• Severe Outcomes 33%
• Differential Methylation 33%
• Acute Perturbation 33%
• Lifetime Exposure 33%
• Trained Immunity 33%
• Methylation Dynamics 33%
• Epigenetic Remodeling 33%
• Clinical Trajectory 33%
• Cumulative Record 33%
• Human Following 33%
• Temporal Trajectory 33%
• Time Since Infection 33%
• Post-acute SARS-CoV-2 33%

Biochemistry, Genetics and Molecular Biology

• Methylation 100%
• SARS Coronavirus 100%
• Immunity 100%
• Epigenetics 40%
• Lifespan 20%
• DNA Methylation 20%
• Dynamics 20%
• Prospective Study 20%
• Differential Gene Expression 20%

Immunology and Microbiology

• Severe Acute Respiratory Syndrome Coronavirus 2 100%
• Methylation 100%
• Immune Dysregulation 100%
• Dynamics 20%
• Inflammatory Disorder 20%
• Lifespan 20%
• DNA Methylation 20%
• Virus 20%
• Differential Gene Expression 20%