A manual, semi-automated and automated ROI study of fMRI hemodynamic response

Jing Zhang, Monte S. Buchsbaum, King Wai Chu, Erin A. Hazlett

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This study is a method comparison of three region-of-interest (ROI) tracing approaches. fMRI images acquired during an event-related frequency discrimination task were used in this study. Three [(1) manual, (2) semi-automated, (3) automated] approaches were applied to generate the ROI in the caudate nucleus and extract fMRI hemodynamic response (HR) from the ROI. Less activation with weak and delayed fMRI HR in the caudate were observed in patients than controls by the 3 approaches, but the manual and automated approaches were more sensitive in detecting such fMRI abnormalities. High correlations of the HR measures were found between the manual and semi-automated ROI approaches, suggesting that the semi-automated approach could be used as an alternative to the manual approach in detecting fMRI experimental effect.

Original languageEnglish
Title of host publicationMEDINFO 2013 - Proceedings of the 14th World Congress on Medical and Health Informatics
PublisherIOS Press
Pages921
Number of pages1
Edition1-2
ISBN (Print)9781614992882
DOIs
StatePublished - 2013
Event14th World Congress on Medical and Health Informatics, MEDINFO 2013 - Copenhagen, Denmark
Duration: 20 Aug 201323 Aug 2013

Publication series

NameStudies in Health Technology and Informatics
Number1-2
Volume192
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference14th World Congress on Medical and Health Informatics, MEDINFO 2013
Country/TerritoryDenmark
CityCopenhagen
Period20/08/1323/08/13

Keywords

  • Automated
  • Region of interest
  • fMRI Hemodynamic response

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