A Human Leukocyte Culture With An Unusual Cytoplasmic Envelopment Of Herpes-Type Particles 1

  • Satish Chandra
  • , Wlo Korol
  • , Richard P. Ames
  • , David P.A. Fabrizio
  • , Erling M. Jensen

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A leukocyte culture, G-6, was established from a pretreatment sample of peripheral blood from a 33-year-old patient with chronic myelogenous leukemia. When studied under time-lapse cinematography, G-6 cells exhibited great surface activity, not observed in other cultured leukocyte cells. A majority of G-6 cells had 45 chromosomes. Herpes-type particles in this culture acquired their envelopes in the cytoplasm of infected cells in a manner not previously reported in any of the established human leukocyte cultures.

Original languageEnglish
Pages (from-to)441-447
Number of pages7
JournalCancer Research
Volume31
Issue number4
StatePublished - Apr 1971
Externally publishedYes

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