A histochemical technique for evaluation of progesterone receptors in breast cancer

L. P. Pertschuk; E. H. Tobin; E. Gaetjens; G. A. Degenshein; L. M. Autuoro; D. J. Brigati; N. D. Bloom; A. C. Carter; E. A. Rainford

A histochemical technique for evaluation of progesterone receptors in breast cancer

L. P. Pertschuk
, E. H. Tobin
, E. Gaetjens
, G. A. Degenshein
, L. M. Autuoro
, D. J. Brigati
, N. D. Bloom
, A. C. Carter
, E. A. Rainford

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A histochemical method for the detection and localization of progesterone receptors in human breast cancer has been developed employing a fluorescein labeled conjugate of bovine serum albumin linked to a progestin as the binding hormone. Considerable tumor cell receptor heterogeneity was apparent and nuclear binding was frequently noted. The results of the new assay correlated with those obtained by dextran-coated charcoal assay in 91 percent of specimens.

Original language	English
Pages (from-to)	635-638
Number of pages	4
Journal	Research Communications in Chemical Pathology and Pharmacology
Volume	23
Issue number	3
State	Published - 1979

Cite this

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title = "A histochemical technique for evaluation of progesterone receptors in breast cancer",

abstract = "A histochemical method for the detection and localization of progesterone receptors in human breast cancer has been developed employing a fluorescein labeled conjugate of bovine serum albumin linked to a progestin as the binding hormone. Considerable tumor cell receptor heterogeneity was apparent and nuclear binding was frequently noted. The results of the new assay correlated with those obtained by dextran-coated charcoal assay in 91 percent of specimens.",

author = "Pertschuk, \{L. P.\} and Tobin, \{E. H.\} and E. Gaetjens and Degenshein, \{G. A.\} and Autuoro, \{L. M.\} and Brigati, \{D. J.\} and Bloom, \{N. D.\} and Carter, \{A. C.\} and Rainford, \{E. A.\}",

year = "1979",

language = "English",

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pages = "635--638",

journal = "Research Communications in Chemical Pathology and Pharmacology",

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T1 - A histochemical technique for evaluation of progesterone receptors in breast cancer

AU - Pertschuk, L. P.

AU - Tobin, E. H.

AU - Gaetjens, E.

AU - Degenshein, G. A.

AU - Autuoro, L. M.

AU - Brigati, D. J.

AU - Bloom, N. D.

AU - Carter, A. C.

AU - Rainford, E. A.

PY - 1979

Y1 - 1979

N2 - A histochemical method for the detection and localization of progesterone receptors in human breast cancer has been developed employing a fluorescein labeled conjugate of bovine serum albumin linked to a progestin as the binding hormone. Considerable tumor cell receptor heterogeneity was apparent and nuclear binding was frequently noted. The results of the new assay correlated with those obtained by dextran-coated charcoal assay in 91 percent of specimens.

AB - A histochemical method for the detection and localization of progesterone receptors in human breast cancer has been developed employing a fluorescein labeled conjugate of bovine serum albumin linked to a progestin as the binding hormone. Considerable tumor cell receptor heterogeneity was apparent and nuclear binding was frequently noted. The results of the new assay correlated with those obtained by dextran-coated charcoal assay in 91 percent of specimens.

UR - https://www.scopus.com/pages/publications/0018397137

M3 - Article

C2 - 461981

AN - SCOPUS:0018397137

SN - 0034-5164

VL - 23

SP - 635

EP - 638

JO - Research Communications in Chemical Pathology and Pharmacology

JF - Research Communications in Chemical Pathology and Pharmacology

IS - 3

ER -

A histochemical technique for evaluation of progesterone receptors in breast cancer

Abstract

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