A genetic analysis of brain volumes and IQ in children

Marieke van Leeuwen, Jiska S. Peper, Stéphanie M. van den Berg, Rachel M. Brouwer, Hilleke E. Hulshoff Pol, René S. Kahn, Dorret I. Boomsma

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown

Original languageEnglish
Pages (from-to)181-191
Number of pages11
Issue number2
StatePublished - Mar 2009
Externally publishedYes


  • Children
  • Gray matter volume
  • Intelligence
  • Twin study
  • White matter volume


Dive into the research topics of 'A genetic analysis of brain volumes and IQ in children'. Together they form a unique fingerprint.

Cite this