A genetic analysis of brain volumes and IQ in children

Marieke van Leeuwen; Jiska S. Peper; Stéphanie M. van den Berg; Rachel M. Brouwer; Hilleke E. Hulshoff Pol; René S. Kahn; Dorret I. Boomsma

doi:10.1016/j.intell.2008.10.005

A genetic analysis of brain volumes and IQ in children

Marieke van Leeuwen, Jiska S. Peper, Stéphanie M. van den Berg, Rachel M. Brouwer, Hilleke E. Hulshoff Pol, René S. Kahn, Dorret I. Boomsma

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown

Original language	English
Pages (from-to)	181-191
Number of pages	11
Journal	Intelligence
Volume	37
Issue number	2
DOIs	https://doi.org/10.1016/j.intell.2008.10.005
State	Published - Mar 2009
Externally published	Yes

Keywords

Children
Gray matter volume
Intelligence
Twin study
White matter volume

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abstract = "In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown",

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T1 - A genetic analysis of brain volumes and IQ in children

AU - van Leeuwen, Marieke

AU - Peper, Jiska S.

AU - van den Berg, Stéphanie M.

AU - Brouwer, Rachel M.

AU - Hulshoff Pol, Hilleke E.

AU - Kahn, René S.

AU - Boomsma, Dorret I.

PY - 2009/3

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AB - In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown

KW - Children

KW - Gray matter volume

KW - Intelligence

KW - Twin study

KW - White matter volume

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VL - 37

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EP - 191

JO - Intelligence

JF - Intelligence

IS - 2

ER -

A genetic analysis of brain volumes and IQ in children

Abstract

Keywords

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