A fluorescent probe for specific detection of cysteine in the lipid dense region of cells

Firoj Ali; H. A. Anila; Nandaraj Taye; Rajesh G. Gonnade; Samit Chattopadhyay; Amitava Das

doi:10.1039/c5cc07450a

A fluorescent probe for specific detection of cysteine in the lipid dense region of cells

Firoj Ali
, H. A. Anila
, Nandaraj Taye
, Rajesh G. Gonnade
, Samit Chattopadhyay
, Amitava Das

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

A new cysteine (Cys) specific chemodosimetric reagent (ER-F) is used in imaging of endogenous Cys localized in the lipid dense region of the live Hct116 cells and the release of Cys within HepG2 cells from a drug following a biochemical transformation. A silica surface, modified with ER-F, could be used for quantitative estimation of Cys present in aqueous solution (pH 7.2) and in a human blood plasma (HBP).

Original language	English
Pages (from-to)	16932-16935
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	95
DOIs	https://doi.org/10.1039/c5cc07450a
State	Published - 24 Sep 2015
Externally published	Yes

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10.1039/c5cc07450a

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title = "A fluorescent probe for specific detection of cysteine in the lipid dense region of cells",

abstract = "A new cysteine (Cys) specific chemodosimetric reagent (ER-F) is used in imaging of endogenous Cys localized in the lipid dense region of the live Hct116 cells and the release of Cys within HepG2 cells from a drug following a biochemical transformation. A silica surface, modified with ER-F, could be used for quantitative estimation of Cys present in aqueous solution (pH 7.2) and in a human blood plasma (HBP).",

author = "Firoj Ali and Anila, \{H. A.\} and Nandaraj Taye and Gonnade, \{Rajesh G.\} and Samit Chattopadhyay and Amitava Das",

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doi = "10.1039/c5cc07450a",

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T1 - A fluorescent probe for specific detection of cysteine in the lipid dense region of cells

AU - Ali, Firoj

AU - Anila, H. A.

AU - Taye, Nandaraj

AU - Gonnade, Rajesh G.

AU - Chattopadhyay, Samit

AU - Das, Amitava

N1 - Publisher Copyright: © The Royal Society of Chemistry.

PY - 2015/9/24

Y1 - 2015/9/24

N2 - A new cysteine (Cys) specific chemodosimetric reagent (ER-F) is used in imaging of endogenous Cys localized in the lipid dense region of the live Hct116 cells and the release of Cys within HepG2 cells from a drug following a biochemical transformation. A silica surface, modified with ER-F, could be used for quantitative estimation of Cys present in aqueous solution (pH 7.2) and in a human blood plasma (HBP).

AB - A new cysteine (Cys) specific chemodosimetric reagent (ER-F) is used in imaging of endogenous Cys localized in the lipid dense region of the live Hct116 cells and the release of Cys within HepG2 cells from a drug following a biochemical transformation. A silica surface, modified with ER-F, could be used for quantitative estimation of Cys present in aqueous solution (pH 7.2) and in a human blood plasma (HBP).

UR - https://www.scopus.com/pages/publications/84947996721

U2 - 10.1039/c5cc07450a

DO - 10.1039/c5cc07450a

M3 - Article

C2 - 26442642

AN - SCOPUS:84947996721

SN - 1359-7345

VL - 51

SP - 16932

EP - 16935

JO - Chemical Communications

JF - Chemical Communications

IS - 95

ER -

A fluorescent probe for specific detection of cysteine in the lipid dense region of cells

Abstract

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