A first update on mapping the human genetic architecture of COVID-19

COVID-19 Host Genetics Initiative; Writing Group; Analysis group; Project management group; Scientific communication group; AncestryDNA COVID-19 Research Study; BelCovid; Biobanque Quebec COVID-19; CCHC COVID-19 GAWS; CHOP CAG; The Colorado Center for Personalized Medicine; Coronagenes; Egypt hgCOVID hub; EraCORE; Estonian Biobank; EXCEED; FinnGen; Functional Host Genomics in Infectious Diseases (FHoGID); RegCOVID; P-PredictUs; SeroCOVID; CRiPSI; GCAT Genomes For Life; GEN-COVID Multicenter Study; Generation Scotland; Genes & Health; Genes & Health Research Team; Genes for Good; Genome-wide assessment of the gene variants associated with severe COVID-19 phenotype in Iran; Host genetic factors in COVID-19 patients in relation to disease susceptibility, disease severity and pharmacogenomics; HUNT; LifeLines; Mass General Brigham-Host Vulnerability to COVID-19; Michigan Genomics Initiative; Mount Sinai Health System COVID-19 Genomics Initiative; MyCode Health Initiative; Netherlands Twin Register; Penn Medicine BioBank; Saudi Human Genome Program-COVID19: Host Genomic markers predicting the severity and suitability to COVID-19 in highly consanguineous population; The genetic predisposition to severe COVID-19; The Norwegian Mother, Father and Child Cohort Study; TwinsUK; UK 100,000 Genomes Project (Genomics England); UK Biobank; UK Blood Donors Cohort; Million Veteran Program; Vanda COVID; Variability in immune response genes and severity of SARS-CoV-2 infection (INMUNGEN-CoV2 study); Women’s Genome Health Stud; Phenotype steering group; COVID-19 HGI

doi:10.1038/s41586-022-04826-7

A first update on mapping the human genetic architecture of COVID-19

COVID-19 Host Genetics Initiative, Writing Group, Analysis group, Project management group, Scientific communication group, AncestryDNA COVID-19 Research Study, BelCovid, Biobanque Quebec COVID-19, CCHC COVID-19 GAWS, CHOP CAG, The Colorado Center for Personalized Medicine, Coronagenes, Egypt hgCOVID hub, EraCORE, Estonian Biobank, EXCEED, FinnGen, Functional Host Genomics in Infectious Diseases (FHoGID), RegCOVID, P-PredictUsSeroCOVID, CRiPSI, GCAT Genomes For Life, GEN-COVID Multicenter Study, Generation Scotland, Genes & Health, Genes & Health Research Team, Genes for Good, Genome-wide assessment of the gene variants associated with severe COVID-19 phenotype in Iran, Host genetic factors in COVID-19 patients in relation to disease susceptibility, disease severity and pharmacogenomics, HUNT, LifeLines, Mass General Brigham-Host Vulnerability to COVID-19, Michigan Genomics Initiative, Mount Sinai Health System COVID-19 Genomics Initiative, MyCode Health Initiative, Netherlands Twin Register, Penn Medicine BioBank, Saudi Human Genome Program-COVID19: Host Genomic markers predicting the severity and suitability to COVID-19 in highly consanguineous population, The genetic predisposition to severe COVID-19, The Norwegian Mother, Father and Child Cohort Study, TwinsUK, UK 100,000 Genomes Project (Genomics England), UK Biobank, UK Blood Donors Cohort, Million Veteran Program, Vanda COVID, Variability in immune response genes and severity of SARS-CoV-2 infection (INMUNGEN-CoV2 study), Women’s Genome Health Stud, Phenotype steering group, COVID-19 HGI

Research output: Contribution to journal › Letter › peer-review

43 Scopus citations

Original language	English
Pages (from-to)	E1-E10
Journal	Nature
Volume	608
Issue number	7921
DOIs	https://doi.org/10.1038/s41586-022-04826-7
State	Published - 4 Aug 2022

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10.1038/s41586-022-04826-7

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COVID-19 Host Genetics Initiative, Writing Group, Analysis group, Project management group, Scientific communication group, AncestryDNA COVID-19 Research Study, BelCovid, Biobanque Quebec COVID-19, CCHC COVID-19 GAWS, CHOP CAG, The Colorado Center for Personalized Medicine, Coronagenes, Egypt hgCOVID hub, EraCORE, Estonian Biobank, EXCEED, FinnGen, Functional Host Genomics in Infectious Diseases (FHoGID), RegCOVID, ... COVID-19 HGI (2022). A first update on mapping the human genetic architecture of COVID-19. Nature, 608(7921), E1-E10. https://doi.org/10.1038/s41586-022-04826-7

@article{beb927c51a9641739d54da032b8fc8fe,

title = "A first update on mapping the human genetic architecture of COVID-19",

author = "{COVID-19 Host Genetics Initiative} and {Writing Group} and {Analysis group} and {Project management group} and {Scientific communication group} and {AncestryDNA COVID-19 Research Study} and BelCovid and {Biobanque Quebec COVID-19} and {CCHC COVID-19 GAWS} and {CHOP CAG} and {The Colorado Center for Personalized Medicine} and Coronagenes and {Egypt hgCOVID hub} and EraCORE and {Estonian Biobank} and EXCEED and FinnGen and {Functional Host Genomics in Infectious Diseases (FHoGID)} and RegCOVID and P-PredictUs and SeroCOVID and CRiPSI and {GCAT Genomes For Life} and {GEN-COVID Multicenter Study} and {Generation Scotland} and {Genes & Health} and {Genes & Health Research Team} and {Genes for Good} and {Genome-wide assessment of the gene variants associated with severe COVID-19 phenotype in Iran} and {Host genetic factors in COVID-19 patients in relation to disease susceptibility, disease severity and pharmacogenomics} and HUNT and LifeLines and {Mass General Brigham-Host Vulnerability to COVID-19} and {Michigan Genomics Initiative} and {Mount Sinai Health System COVID-19 Genomics Initiative} and {MyCode Health Initiative} and {Netherlands Twin Register} and {Penn Medicine BioBank} and {Saudi Human Genome Program-COVID19: Host Genomic markers predicting the severity and suitability to COVID-19 in highly consanguineous population} and {The genetic predisposition to severe COVID-19} and {The Norwegian Mother, Father and Child Cohort Study} and TwinsUK and {UK 100,000 Genomes Project (Genomics England)} and {UK Biobank} and {UK Blood Donors Cohort} and {Million Veteran Program} and {Vanda COVID} and {Variability in immune response genes and severity of SARS-CoV-2 infection (INMUNGEN-CoV2 study)} and {Women{\textquoteright}s Genome Health Stud} and {Phenotype steering group} and {COVID-19 HGI} and Pathak, {Gita A.} and Juha Karjalainen and Christine Stevens and Neale, {Benjamin M.} and Mark Daly and Andrea Ganna and Andrews, {Shea J.} and Masahiro Kanai and Mattia Cordioli and Renato Polimanti and Nadia Harerimana and Matti Pirinen and Liao, {Rachel G.} and Karolina Chwialkowska and Amy Trankiem and Balaconis, {Mary K.} and Huy Nguyen and Matthew Solomonson and Kumar Veerapen and Brooke Wolford and Genevieve Roberts and Danny Park and Ball, {Catherine A.} and Marie Coignet and Shannon McCurdy and Spencer Knight and Raghavendran Partha and Brooke Rhead and Miao Zhang and Nathan Berkowitz and Michael Gaddis and Keith Noto and Luong Ruiz and Milos Pavlovic and Hong, {Eurie L.} and Sebra, {Robert P.} and Sealfon, {Stuart C.} and Jordan, {Daniel M.} and Kumardeep Chaudhary and Belbin, {Gillian M.} and Michael Preuss and Clive Hoggart and Charney, {Alexander W.} and Beckmann, {Noam D.} and Abul-Husn, {Noura S.} and Yuval Itan and Kenny, {Eimear E.} and Nadkarni, {Girish N.} and Ron Do and Huckins, {Laura M.}",

year = "2022",

month = aug,

day = "4",

doi = "10.1038/s41586-022-04826-7",

language = "English",

volume = "608",

pages = "E1--E10",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "7921",

}

COVID-19 Host Genetics Initiative, Writing Group, Analysis group, Project management group, Scientific communication group, AncestryDNA COVID-19 Research Study, BelCovid, Biobanque Quebec COVID-19, CCHC COVID-19 GAWS, CHOP CAG, The Colorado Center for Personalized Medicine, Coronagenes, Egypt hgCOVID hub, EraCORE, Estonian Biobank, EXCEED, FinnGen, Functional Host Genomics in Infectious Diseases (FHoGID), RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, GCAT Genomes For Life, GEN-COVID Multicenter Study, Generation Scotland, Genes & Health, Genes & Health Research Team, Genes for Good, Genome-wide assessment of the gene variants associated with severe COVID-19 phenotype in Iran, Host genetic factors in COVID-19 patients in relation to disease susceptibility, disease severity and pharmacogenomics, HUNT, LifeLines, Mass General Brigham-Host Vulnerability to COVID-19, Michigan Genomics Initiative, Mount Sinai Health System COVID-19 Genomics Initiative, MyCode Health Initiative, Netherlands Twin Register, Penn Medicine BioBank, Saudi Human Genome Program-COVID19: Host Genomic markers predicting the severity and suitability to COVID-19 in highly consanguineous population, The genetic predisposition to severe COVID-19, The Norwegian Mother, Father and Child Cohort Study, TwinsUK, UK 100,000 Genomes Project (Genomics England), UK Biobank, UK Blood Donors Cohort, Million Veteran Program, Vanda COVID, Variability in immune response genes and severity of SARS-CoV-2 infection (INMUNGEN-CoV2 study), Women’s Genome Health Stud, Phenotype steering group & COVID-19 HGI 2022, 'A first update on mapping the human genetic architecture of COVID-19', Nature, vol. 608, no. 7921, pp. E1-E10. https://doi.org/10.1038/s41586-022-04826-7

TY - JOUR

T1 - A first update on mapping the human genetic architecture of COVID-19

AU - COVID-19 Host Genetics Initiative

AU - Writing Group

AU - Analysis group

AU - Project management group

AU - Scientific communication group

AU - AncestryDNA COVID-19 Research Study

AU - BelCovid

AU - Biobanque Quebec COVID-19

AU - CCHC COVID-19 GAWS

AU - CHOP CAG

AU - The Colorado Center for Personalized Medicine

AU - Coronagenes

AU - Egypt hgCOVID hub

AU - EraCORE

AU - Estonian Biobank

AU - EXCEED

AU - FinnGen

AU - Functional Host Genomics in Infectious Diseases (FHoGID)

AU - RegCOVID

AU - P-PredictUs

AU - SeroCOVID

AU - CRiPSI

AU - GCAT Genomes For Life

AU - GEN-COVID Multicenter Study

AU - Generation Scotland

AU - Genes & Health

AU - Genes & Health Research Team

AU - Genes for Good

AU - Genome-wide assessment of the gene variants associated with severe COVID-19 phenotype in Iran

AU - Host genetic factors in COVID-19 patients in relation to disease susceptibility, disease severity and pharmacogenomics

AU - HUNT

AU - LifeLines

AU - Mass General Brigham-Host Vulnerability to COVID-19

AU - Michigan Genomics Initiative

AU - Mount Sinai Health System COVID-19 Genomics Initiative

AU - MyCode Health Initiative

AU - Netherlands Twin Register

AU - Penn Medicine BioBank

AU - Saudi Human Genome Program-COVID19: Host Genomic markers predicting the severity and suitability to COVID-19 in highly consanguineous population

AU - The genetic predisposition to severe COVID-19

AU - The Norwegian Mother, Father and Child Cohort Study

AU - TwinsUK

AU - UK 100,000 Genomes Project (Genomics England)

AU - UK Biobank

AU - UK Blood Donors Cohort

AU - Million Veteran Program

AU - Vanda COVID

AU - Variability in immune response genes and severity of SARS-CoV-2 infection (INMUNGEN-CoV2 study)

AU - Women’s Genome Health Stud

AU - Phenotype steering group

AU - COVID-19 HGI

AU - Pathak, Gita A.

AU - Karjalainen, Juha

AU - Stevens, Christine

AU - Neale, Benjamin M.

AU - Daly, Mark

AU - Ganna, Andrea

AU - Andrews, Shea J.

AU - Kanai, Masahiro

AU - Cordioli, Mattia

AU - Polimanti, Renato

AU - Harerimana, Nadia

AU - Pirinen, Matti

AU - Liao, Rachel G.

AU - Chwialkowska, Karolina

AU - Trankiem, Amy

AU - Balaconis, Mary K.

AU - Nguyen, Huy

AU - Solomonson, Matthew

AU - Veerapen, Kumar

AU - Wolford, Brooke

AU - Roberts, Genevieve

AU - Park, Danny

AU - Ball, Catherine A.

AU - Coignet, Marie

AU - McCurdy, Shannon

AU - Knight, Spencer

AU - Partha, Raghavendran

AU - Rhead, Brooke

AU - Zhang, Miao

AU - Berkowitz, Nathan

AU - Gaddis, Michael

AU - Noto, Keith

AU - Ruiz, Luong

AU - Pavlovic, Milos

AU - Hong, Eurie L.

AU - Sebra, Robert P.

AU - Sealfon, Stuart C.

AU - Jordan, Daniel M.

AU - Chaudhary, Kumardeep

AU - Belbin, Gillian M.

AU - Preuss, Michael

AU - Hoggart, Clive

AU - Charney, Alexander W.

AU - Beckmann, Noam D.

AU - Abul-Husn, Noura S.

AU - Itan, Yuval

AU - Kenny, Eimear E.

AU - Nadkarni, Girish N.

AU - Do, Ron

AU - Huckins, Laura M.

PY - 2022/8/4

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DO - 10.1038/s41586-022-04826-7

M3 - Letter

C2 - 35922517

AN - SCOPUS:85135433188

SN - 0028-0836

VL - 608

SP - E1-E10

JO - Nature

JF - Nature

IS - 7921

ER -