A devastating ocular pathogen: β-streptococcus group G

David C. Ritterband, Mahendra K. Shah, Douglas J. Buxton, Myrna C. Intal, Debra S. Guthrie, John A. Seedor

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Purpose. To report the clinical findings, treatment, and outcomes of four cases of β-streptococcus Group G (BHS-G) ocular infection. Methods. The medical and microbiologic records of four cases of BHS-G ocular infection were retrospectively reviewed. Results. Two cases of BHS-G endophthalmitis and two cases of BHS-G keratitis were recorded. Three patients developed fulminant infection within 12 hours of the onset of symptoms. One patient's history was incomplete. One patient developed endophthalmitis from a contaminated donor button; another following cataract surgery. One developed keratitis in a keratoplasty suture tract; and another patient developed a corneal abscess after being struck with a tree branch. The patient with the contaminated donor button developed overwhelming endophthalmitis resulting in no light perception vision, severe pain, and evisceration. The postoperative cataract patient developed a purulent endophthalmitis and is still hypotonus with light perception vision. The second keratitis patient developed a significant suture abscess with marked stromal loss but eventually healed. The traumatic keratitis patient developed a large ulcer with hypopyon and descemetocele but was lost to follow-up. Conclusions. This is the first report of a series of BHS-G ocular infections. The ocular infections were characterized by rapid onset, extreme inflammation, and - despite in vitro antibiotic sensitivity - a poor or sluggish response to antibiotic therapy.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
Issue number3
StatePublished - May 2000
Externally publishedYes


  • Endophthalmitis
  • Keratitis
  • Lancefield group G
  • β-streptococcus


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