A comprehensive review of coronary artery disease in patients with end-stage liver disease

Michael Dangl; Trevor Eisenberg; Jelani K. Grant; Louis Vincent; Rosario Colombo; Rhea Sancassani; Joao Braghiroli; Paul Martin; Rodrigo Vianna; Ramona Nicolau-Raducu; Cesar Mendoza

doi:10.1016/j.trre.2022.100709

A comprehensive review of coronary artery disease in patients with end-stage liver disease

Michael Dangl, Trevor Eisenberg, Jelani K. Grant, Louis Vincent, Rosario Colombo, Rhea Sancassani, Joao Braghiroli, Paul Martin, Rodrigo Vianna, Ramona Nicolau-Raducu, Cesar Mendoza

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The prevalence of coronary artery disease has increased in patients with end stage liver disease. In the near future, non-alcoholic steatohepatitis is expected to be the leading cause of end stage liver disease and shares common risk factors with coronary artery disease such as hypertension, hyperlipidemia, obesity and diabetes mellitus. At present, liver transplantation is the only definitive treatment for end stage liver disease, with post-operative mortality associated with the presence of coronary artery disease. Given the high prevalence of cardiovascular disease and the unique balance of pro-thrombotic and antithrombotic factors in patients with end stage liver disease, we sought to discuss the non-invasive and invasive diagnosis, medical and procedural management considerations and pre-transplant evaluation of coronary artery disease in patients with end stage liver disease.

Original language	English
Article number	100709
Journal	Transplantation Reviews
Volume	36
Issue number	3
DOIs	https://doi.org/10.1016/j.trre.2022.100709
State	Published - Jul 2022
Externally published	Yes

Keywords

Coronary artery disease
Coronary artery imaging
End-stage liver disease
Liver transplantation
Non-invasive coronary artery screening
Percutaneous coronary intervention
Pretransplantation evaluation

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10.1016/j.trre.2022.100709

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title = "A comprehensive review of coronary artery disease in patients with end-stage liver disease",

abstract = "The prevalence of coronary artery disease has increased in patients with end stage liver disease. In the near future, non-alcoholic steatohepatitis is expected to be the leading cause of end stage liver disease and shares common risk factors with coronary artery disease such as hypertension, hyperlipidemia, obesity and diabetes mellitus. At present, liver transplantation is the only definitive treatment for end stage liver disease, with post-operative mortality associated with the presence of coronary artery disease. Given the high prevalence of cardiovascular disease and the unique balance of pro-thrombotic and antithrombotic factors in patients with end stage liver disease, we sought to discuss the non-invasive and invasive diagnosis, medical and procedural management considerations and pre-transplant evaluation of coronary artery disease in patients with end stage liver disease.",

keywords = "Coronary artery disease, Coronary artery imaging, End-stage liver disease, Liver transplantation, Non-invasive coronary artery screening, Percutaneous coronary intervention, Pretransplantation evaluation",

author = "Michael Dangl and Trevor Eisenberg and Grant, {Jelani K.} and Louis Vincent and Rosario Colombo and Rhea Sancassani and Joao Braghiroli and Paul Martin and Rodrigo Vianna and Ramona Nicolau-Raducu and Cesar Mendoza",

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doi = "10.1016/j.trre.2022.100709",

language = "English",

volume = "36",

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AU - Dangl, Michael

AU - Eisenberg, Trevor

AU - Grant, Jelani K.

AU - Vincent, Louis

AU - Colombo, Rosario

AU - Sancassani, Rhea

AU - Braghiroli, Joao

AU - Martin, Paul

AU - Vianna, Rodrigo

AU - Nicolau-Raducu, Ramona

AU - Mendoza, Cesar

PY - 2022/7

Y1 - 2022/7

N2 - The prevalence of coronary artery disease has increased in patients with end stage liver disease. In the near future, non-alcoholic steatohepatitis is expected to be the leading cause of end stage liver disease and shares common risk factors with coronary artery disease such as hypertension, hyperlipidemia, obesity and diabetes mellitus. At present, liver transplantation is the only definitive treatment for end stage liver disease, with post-operative mortality associated with the presence of coronary artery disease. Given the high prevalence of cardiovascular disease and the unique balance of pro-thrombotic and antithrombotic factors in patients with end stage liver disease, we sought to discuss the non-invasive and invasive diagnosis, medical and procedural management considerations and pre-transplant evaluation of coronary artery disease in patients with end stage liver disease.

AB - The prevalence of coronary artery disease has increased in patients with end stage liver disease. In the near future, non-alcoholic steatohepatitis is expected to be the leading cause of end stage liver disease and shares common risk factors with coronary artery disease such as hypertension, hyperlipidemia, obesity and diabetes mellitus. At present, liver transplantation is the only definitive treatment for end stage liver disease, with post-operative mortality associated with the presence of coronary artery disease. Given the high prevalence of cardiovascular disease and the unique balance of pro-thrombotic and antithrombotic factors in patients with end stage liver disease, we sought to discuss the non-invasive and invasive diagnosis, medical and procedural management considerations and pre-transplant evaluation of coronary artery disease in patients with end stage liver disease.

KW - Coronary artery disease

KW - Coronary artery imaging

KW - End-stage liver disease

KW - Liver transplantation

KW - Non-invasive coronary artery screening

KW - Percutaneous coronary intervention

KW - Pretransplantation evaluation

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DO - 10.1016/j.trre.2022.100709

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VL - 36

JO - Transplantation Reviews

JF - Transplantation Reviews

IS - 3

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ER -

A comprehensive review of coronary artery disease in patients with end-stage liver disease

Abstract

Keywords

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