A CD4-CDR3 Peptide Analog Inhibits Both Primary and Secondary Autoreactive CD4⁺ T Cell Responses in Experimental Allergic Encephalomyelitis

Keyphrases

• Complementarity-determining Region 3 (CDR3) 100%
• CD4+ T 100%
• Peptide Analogs 100%
• Cell Response 100%
• Experimental Autoimmune Encephalomyelitis 100%
• Autoreactive 100%
• T Cells 33%
• Alloantigen 33%
• Autoimmune 16%
• Disease Stage 16%
• Lymphocytes 16%
• Interleukin-4 (IL-4) 16%
• T Cell Response 16%
• Normal Response 16%
• CD4+ T Cells 16%
• Lymph Node 16%
• Mouse Model 16%
• Pathologic 16%
• Cell-mediated 16%
• Therapeutic Approaches 16%
• Autoreactive T Cells 16%
• As(V) 16%
• Effective Dose 16%
• Keyhole Limpet Hemocyanin 16%
• SJL Mice 16%
• PLP1 16%
• Cytokine Profile 16%
• Toxic Effects 16%
• Primary Response 16%
• Structure-based Design 16%
• Rechallenge 16%
• Autoimmune Response 16%
• Secondary Response 16%
• Potential Inhibitors 16%
• Design Approach 16%
• Cyclized Peptide 16%
• Long-term Resistance 16%

Immunology and Microbiology

• CD4 100%
• T-Helper Cell 100%
• Experimental Autoimmune Encephalomyelitis 100%
• T Cell 66%
• Alloantigen 33%
• Autoimmunity 16%
• Interleukin 4 16%
• Cytokine 16%
• Lymph Node 16%
• Mouse Model 16%
• Keyhole Limpet Hemocyanin 16%
• Swiss James Lambert Mouse 16%
• Lymphocyte 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Experimental Autoimmune Encephalomyelitis 100%
• Alloantigen 33%
• Disease 16%
• Cytokine 16%
• Interleukin 4 16%
• Mouse Model 16%
• Toxicity 16%
• Swiss James Lambert Mouse 16%
• Proteolipid Protein 16%
• Keyhole Limpet Hemocyanin 16%