A Blood-Bile Glucose Barrier in Man

Clarence J. Schein, Barnett Zumoff, Jacob Kream, Joseph Cassouto, Leon Hellman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Utilizing a glucose oxidase analytical method, free glucose has been found to be virtually absent from human bile, both in the normoglycemic state and during induced hyperglycemia. In contrast, orally administered xylose appears in bile in concentrations similar to those of plasma. These results suggest a physiologically determined blood-bile barrier for glucose in man. Possible mechanisms for this phenomenon are discussed.

Original languageEnglish
Pages (from-to)1094-1097
Number of pages4
Issue number6
StatePublished - 1968
Externally publishedYes


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