A Blood-Bile Glucose Barrier in Man

Clarence J. Schein; Barnett Zumoff; Jacob Kream; Joseph Cassouto; Leon Hellman

doi:10.1016/S0016-5085(68)80129-5

A Blood-Bile Glucose Barrier in Man

Clarence J. Schein, Barnett Zumoff, Jacob Kream, Joseph Cassouto, Leon Hellman

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Utilizing a glucose oxidase analytical method, free glucose has been found to be virtually absent from human bile, both in the normoglycemic state and during induced hyperglycemia. In contrast, orally administered xylose appears in bile in concentrations similar to those of plasma. These results suggest a physiologically determined blood-bile barrier for glucose in man. Possible mechanisms for this phenomenon are discussed.

Original language	English
Pages (from-to)	1094-1097
Number of pages	4
Journal	Gastroenterology
Volume	54
Issue number	6
DOIs	https://doi.org/10.1016/S0016-5085(68)80129-5
State	Published - 1968
Externally published	Yes

Access to Document

10.1016/S0016-5085(68)80129-5

Cite this

@article{63d7c29ed05d4ee2afd1497a9a67d4f6,

title = "A Blood-Bile Glucose Barrier in Man",

abstract = "Utilizing a glucose oxidase analytical method, free glucose has been found to be virtually absent from human bile, both in the normoglycemic state and during induced hyperglycemia. In contrast, orally administered xylose appears in bile in concentrations similar to those of plasma. These results suggest a physiologically determined blood-bile barrier for glucose in man. Possible mechanisms for this phenomenon are discussed.",

author = "Schein, {Clarence J.} and Barnett Zumoff and Jacob Kream and Joseph Cassouto and Leon Hellman",

year = "1968",

doi = "10.1016/S0016-5085(68)80129-5",

language = "English",

volume = "54",

pages = "1094--1097",

journal = "Gastroenterology",

issn = "0016-5085",

publisher = "W.B. Saunders Ltd",

number = "6",

}

TY - JOUR

T1 - A Blood-Bile Glucose Barrier in Man

AU - Schein, Clarence J.

AU - Zumoff, Barnett

AU - Kream, Jacob

AU - Cassouto, Joseph

AU - Hellman, Leon

PY - 1968

Y1 - 1968

N2 - Utilizing a glucose oxidase analytical method, free glucose has been found to be virtually absent from human bile, both in the normoglycemic state and during induced hyperglycemia. In contrast, orally administered xylose appears in bile in concentrations similar to those of plasma. These results suggest a physiologically determined blood-bile barrier for glucose in man. Possible mechanisms for this phenomenon are discussed.

AB - Utilizing a glucose oxidase analytical method, free glucose has been found to be virtually absent from human bile, both in the normoglycemic state and during induced hyperglycemia. In contrast, orally administered xylose appears in bile in concentrations similar to those of plasma. These results suggest a physiologically determined blood-bile barrier for glucose in man. Possible mechanisms for this phenomenon are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0014297924&partnerID=8YFLogxK

U2 - 10.1016/S0016-5085(68)80129-5

DO - 10.1016/S0016-5085(68)80129-5

M3 - Article

C2 - 5656328

AN - SCOPUS:0014297924

VL - 54

SP - 1094

EP - 1097

JO - Gastroenterology

JF - Gastroenterology

SN - 0016-5085

IS - 6

ER -

A Blood-Bile Glucose Barrier in Man

Abstract

Access to Document

Fingerprint

Cite this