2013. Draft genome sequence of Escherichia coli strain ATCC 23502, serovar O5:K4:H4

Brady F. Cress; Zachary R. Greene; Robert J. Linhardt; Mattheos A.G. Koffas

doi:10.1128/genomeA.00046-13

2013. Draft genome sequence of Escherichia coli strain ATCC 23502, serovar O5:K4:H4

Brady F. Cress, Zachary R. Greene, Robert J. Linhardt, Mattheos A.G. Koffas

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.

Original language	English
Article number	e00046-13
Journal	Genome Announcements
Volume	1
Issue number	2
DOIs	https://doi.org/10.1128/genomeA.00046-13
State	Published - 2013
Externally published	Yes

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abstract = "We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.",

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AU - Linhardt, Robert J.

AU - Koffas, Mattheos A.G.

PY - 2013

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AB - We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.

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2013. Draft genome sequence of Escherichia coli strain ATCC 23502, serovar O5:K4:H4

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