1-Benzyl-1,4-diazepan-5-one

Fei Sha, Hao Xu, Shan Liu, Peng Wang, Jin Tang Wang

Research output: Contribution to journalArticlepeer-review

Abstract

The title compound, C12H16N2O, is a diazepane inter-mediate that can be used as an inhibitor of human nitric oxide synthesis. In the mol-ecule, the seven-membered ring has a chair-like conformation and the two rings are approximately perpendicular to one another, with a C - N - C - C torsion angle of 77.8 (4)°. Inter-molecular N - H⋯O hydrogen bonds link the mol-ecules into dimers around a centre of symmetry, with C - H⋯O inter-actions linking the dimers into infinite sheets.

Original languageEnglish
Pages (from-to)o569
JournalActa Crystallographica Section E: Structure Reports Online
Volume64
Issue number3
DOIs
StatePublished - 2008
Externally publishedYes

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