槲 皮素 对 动 物 肠道 黏 膜 屏障 功 能 的影 响 及其 调 控 机 制

Translated title of the contribution: Effects and Regulatory Mechanisms of Quercetin on Animal Intestinal Mucosal Barrier Function

Huadi Mei, Yuanfei Li, Xianyong Ma, Miao Yu

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The intestinal mucosa is the medium of communication between the internal body environment and outside world, and is the first line of host defense. Therefore, the integrity of intestinal mucosal barrier is essential for maintaining intestinal homeostasis and even host health. Quercetin is a natural flavonoids compound, which has anti-inflammatory, anti-oxidant, anti-cancer and anti-bacterial functions. Researches showed that quercetin may maintain intestinal homeostasis and body health by regulating the composition of intestinal microbes, the thickness of mucus layer, the expression of tight junction proteins in intestinal epithelial cells, the production of bile and antimicrobial peptides, and the secretion of cytokine. The present study mainly reviewed the mechanism of quercetin regulating the intestinal mucosal barrier function in animals, this will provide a theoretical basis for developing new feed additives and their application in livestock and poultry production.

Translated title of the contributionEffects and Regulatory Mechanisms of Quercetin on Animal Intestinal Mucosal Barrier Function
Original languageChinese (Traditional)
Pages (from-to)5475-5488
Number of pages14
JournalChinese Journal of Animal Nutrition
Volume34
Issue number9
DOIs
StatePublished - 15 Sep 2022
Externally publishedYes

Keywords

  • absorption and metabolism
  • mechanism
  • mucosal barrier
  • quercetin
  • regulation

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