Abstract
Transcripts encoding the cysteine-proteinase inhibitor rat cystatin S are induced in submandibular and parotid glands by the β-adrenergic agonist isoproterenol (isoprenaline). High levels of cystatin S mRNA persist in glands of chronically treated animals for 6 days after discontinuation of the catecholamine, indicating a long half-life of the mRNA. Post-transcriptionally the size of the mRNA decreases, owing to a shortening of the poly(A) tail.
| Original language | English |
|---|---|
| Pages (from-to) | 685-689 |
| Number of pages | 5 |
| Journal | Biochemical Journal |
| Volume | 257 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1989 |