Épigénétique: Un lien entre l'environnement et le génome

Translated title of the contribution: Epigenetic: A link between environment and genome

Benoit Labonté, Gustavo Turecki

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Adversity during childhood has for long been known to increase the risk of developing mental health problems in adulthood. Yet, it is only recently that epigenetic mechanisms have been identified as representing an interface on which the environment acts upon to induce behavioral changes. These changes affecting the expression of certain genes, without however modifying DNA sequences, particularly interfere with the functioning of systems regulating response to stress. In the long term, adversity during childhood, by inducing these epigenetic changes, predisposes some individuals in developing mental health problems in adulthood. This article examines the epigenetic impact of adversity during childhood and its behavioral consequences on mental health.

Translated title of the contributionEpigenetic: A link between environment and genome
Original languageFrench
Pages (from-to)31-44
Number of pages14
JournalSante Mentale au Quebec
Volume37
Issue number2
DOIs
StatePublished - 2012
Externally publishedYes

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