LILRB modulates tumor microenvironment and promotes tumor progression

Project Details

Description

Project Narrative T myeloid-derived suppressor cells (MDSC) are responsible for supporting an environment that promotes cancer progression and invasion. The goal of our project is to understand the mechanism underlying the regulation of Tumor associate macrophage (TAM)/MDSC pro-tumor and tumor invasion by LILRB. The results from this study will be used to design TAM/MDSC-targeted cancer immune therapies.
StatusFinished
Effective start/end date1/12/1630/11/22

Funding

  • National Cancer Institute: $435,587.00
  • National Cancer Institute: $1,743,495.00
  • National Cancer Institute: $1.00
  • National Cancer Institute: $457,636.00

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.