Research output per year
Research output per year
Personal profile
Headline
PROFESSOR | Neurology, Neuroscience
Biography
Molecular, Cellular, Behavioral Biology and Translational Research in Neurodegeneration Our long-term goal is to understand the molecular and cellular mechanisms of neurodegeneration that causes human neurological disorders such as Parkinson’s, Huntington’s and Alzheimer’s diseases. Our mission is to translate our knowledge from basic research to the development of molecular diagnostics and therapeutics for neurological disorders. Our primary research interests encompass molecular and cellular pathways for autophagy-lysosome degradation, protein quality control (aggregate clearance), synaptic vesicle trafficking, neuroinflammation, and protein/lipid kinase signaling in neuropathogenesis. Other Web Sites http://www.mountsinai.org/Research/Centers%20Laboratories%20and%20Programs/Yue%20Laboratory Yue Laboratory Multi-Disciplinary Training Areas Biophysics and Systems Pharmacology [BSP], Neuroscience [NEU]
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Collaborations and top research areas from the last five years
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Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence
Choi, I., Wang, M., Yoo, S., Xu, P., Seegobin, S. P., Li, X., Han, X., Wang, Q., Peng, J., Zhang, B. & Yue, Z., Jul 2023, In: Nature Cell Biology. 25, 7, p. 963-974 12 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Cell type-specific NRBF2 orchestrates autophagic flux and adult hippocampal neurogenesis in chronic stress-induced depression
Zhang, S. Q., Deng, Q., Zhu, Q., Hu, Z. L., Long, L. H., Wu, P. F., He, J. G., Chen, H. S., Yue, Z., Lu, J. H., Wang, F. & Chen, J. G., Dec 2023, In: Cell Discovery. 9, 1, 90.Research output: Contribution to journal › Article › peer-review
Open Access -
Gut bacterial profiles in Parkinson's disease: A systematic review
Li, Z., Liang, H., Hu, Y., Lu, L., Zheng, C., Fan, Y., Wu, B., Zou, T., Luo, X., Zhang, X., Zeng, Y., Liu, Z., Zhou, Z., Yue, Z., Ren, Y., Li, Z., Su, Q. & Xu, P., Jan 2023, In: CNS Neuroscience and Therapeutics. 29, 1, p. 140-157 18 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Emerging roles of NRBF2/PI3KC3 axis in maintaining homeostasis of brain and guts
Wu, M. Y., Cai, C. Z., Yang, C., Yue, Z., Chen, Y., Bian, Z. X., Li, M. & Lu, J. H., Feb 2022, In: Neural Regeneration Research. 17, 2, p. 323-324 2 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models
Cai, C. Z., Zhuang, X. X., Zhu, Q., Wu, M. Y., Su, H., Wang, X. J., Iyaswamy, A., Yue, Z., Wang, Q., Zhang, B., Xue, Y., Tan, J., Li, M., He, H. & Lu, J. H., 2022, In: Theranostics. 12, 4, p. 1738-1755 18 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations